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COVID-19 Scientific and Public Health Policy Update (22 September 2020)

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A. Executive summary ● Two studies report on a possibility of in-flight transmission of SARS-COV-2 over long commercial flights among passengers and flight attendants. The studies suggest that guidelines for preventing SARS-CoV-2 infection among passengers should consider individual passengers’ risk for infection, the number of passengers traveling, and flight duration. ● A study reports on an in-depth analysis of the SARS-CoV-2 landscape in Africa and identifying distinguishing mutations in the African SARS-CoV-2 genomes. Results showed a similarity between the African SARS-CoV-2 genomes and genomes in other countries. ● A prospective cohort study assessed outcome of patients with moderate and severe COVID-19 following treatment with convalescent plasma (CP). Findings suggest that treatment with CP with higher levels of IgG against S1 may benefit patients with moderate and severe COVID-19. ● This study aimed to identify what the additional health-care costs of a strategic preparedness and response plan in 73 low-income and middle-income countries. Findings suggest that the total cost estimate for the COVID-19 response in the status quo scenario was US$52·45 billion over 4 weeks, at $8·60 per capita. For the decreased or increased transmission scenarios, the totals were $33·08 billion and $61·92 billion, respectively. ● A mathematical model for the COVID-19 in Cameroon, incorporates some key epidemiological and biological features of the disease. Findings suggest that isolation has a real impact on limiting COVID-19 transmission.

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Africa CDC
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